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Sjogern's versus multiple sclerosis


#1

Hi guys. Just wondered if anyone here had any thoughts on sjogerns versus multiple sclersosis? I have read recently that two are quite similar and my aunt has MS. I was thinking that it could be possible that I could actually have MS and not sjogerns? Or both? I have literally just seen a rheumatologist who actually didn’t just suggest that my extremely high inflammation markers were as a result of me being overweight, given that I have lost 35 kilos over the last year and the symptoms are as bad as ever. I am hoping he might have some insight.


#2

Anything’s possible, and there’s a pretty big overlap in terms of symptoms. Not a scientific paper, but interesting reading - http://scarysymptoms.com/2012/02/multiple-sclerosis-vs-sjogrens-syndrome/

Another interesting paper showing the issue differentiating between the two - https://www.omicsonline.org/open-access/gougerot-sjgren-syndrome-mimicking-multiple-sclerosis-2■■■■-1000175.php?aid=62724

The point? It can be hard to distinguish when there’s neurological involvement. Have you had a full panel for autoimmune disorders including SSA and SSB? Lip biopsy? Tear test? These can help point towards Sjogren’s.


#3

My blood work is negative but my tear test showed reduced production. I am hoping to avoid the lip biopsy


#4

I’m sero negative but have avoided the lip biopsy. I’ve also avoided the nerve biopsy to definitively diagnose small fiber neuropathy. In either case, the information gained wouldn’t change my management so they’re unnecessary.