I would like to propose a new single thread (discussion) that includes all references. links and new research papers that pertain to Sjogren's.
This would keep it all in one place and make it easier for members and particulary new members to find such information without having to search all discussions and then search each one singly to find references.
Perhaps Dryguy and Kazzcass would like to comment please as they seem to be most active in searching for new developments?
I shall start with
a good introduction by the world leading Sjogren's expert.
Here is his website a good start point for fellow searchers after the truth, treatment and a cure.
I attach one powerpoint presentation from him, I can't attach the other as it is too large.However here is a link to download it for yourself
The theme is the interaction of the immune response and the nervous system.
This is the area that most interests and excites me, as it is in my opinion, the area most likely to provide possible short term treatment of Sjogren's if only someone would follow up the basic research with applied research into treatments. A cure will be more difficult sadly.
I firmly believe that many of the effects of Sjogren's are due to the production of auto antibodies to the M3 receptors which then impact on the neurotransmitters (acetyl choline) and prevent functioning of the exocrine glands and also causes the pains, cystitis and fatigue that we suffer.
The main researcher in this field is Professor Tom Gordon in Australia, unfortunately he has not answered any of my emails so far ( if any of our Australian members would like to help please pm me).
A very modern paper on this area originally in Japanese - any Japanese members like to contact the authors? It seems Japan, China and Australia are the only countries doing any significant research into autoimmunity and serology particularly Sjogren's.
These autoanti-bodies may also be relevent to Lupus and scleroderma, MS and fibromyalgia.
I hope the attached and this thread are of help to my fellow sufferers of this dreadful disease and the ignorance of the medics :) Keep fighting ignorance and push your medics to read these articles and look at these presentations and follow them up!!!
Best wishes to all Mike80-Kyoto__2013.pptx (2.7 MB)