Recruiting participants for research study on Baminercept in Sjögren's Syndrome

Hi Guys,
National Institute of Allergy and Infectious Diseases (NIAID) is advertising that it is recruiting for a study on Baminercept in Sjögren's Syndrome
Please note that Bens Friends is no way involved with this study.Anyone interested should contact one of the prinicipal investigators - details given below
Estimated completion date September 2014

Sjögren's syndrome is an autoimmune disorder in which a person's own immune cells attack the body's tear and salivary glands. This disease is the second most common autoimmune disorder, affects close to four million people in the U.S., and has no known cause. About one-third of patients with Sjögren's syndrome have enlarged parotid glands (the largest salivary glands, the glands that make saliva); inflammation of organs such as the lungs and joints may also occur. There is no known effective treatment other than measures that can relieve symptoms. One of the most bothersome symptoms is dryness of the eyes and mouth. Eye drops and saliva stimulants (which help make more saliva) are common treatments. When other organs are affected, symptoms are treated with corticosteroids (prednisone), non-steroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen and naproxen), hydroxychloroquine (Plaquenil®) or other medications that suppress the immune system. These drugs may curb or kill cells of the immune system, but they are not always helpful, do not cure Sjögren's syndrome, and can have many side effects.

The purpose of the study is to find out if the experimental study agent, baminercept, is effective in treating patients with Sjögren's syndrome. The study will also determine if the study agent can be safely given to patients with Sjögren's syndrome; examine how it affects symptoms of the disease; and attempt to understand how baminercept affects the underlying mechanisms of Sjögren's syndrome and the immune system.

Please refer to this study by its identifier: NCT01552681

United States, California
Cedars-Sinai Medical Center Recruiting
Los Angeles, California, United States, 90048

Contact: Erin Avila 310-423-2979

Principal Investigator: Daniel Wallace, MD
Stanford University Recruiting
Palo Alto, California, United States, 94304

Contact: Mark Genovese, MD 650-498-4528

Contact: Jennifer Hillygus-Kanerva (650) 723-7416
Principal Investigator: Mark Genovese, MD
United States, Connecticut
St. Francis Hospital and Medical Center Recruiting
Hartford, Connecticut, United States, 06105

Contact: Betsy Keller, RN 860-714-4555

Contact: Ann Parke, MD (860) 714-5816
Principal Investigator: Ann Parke, MD
United States, Illinois
University of Chicago Recruiting
Chicago, Illinois, United States, 60637

Contact: Elizabeth Yan 773-834-5357

Principal Investigator: Tammy Utset, MD
United States, Maryland
Johns Hopkins Medical Institute Recruiting
Baltimore, Maryland, United States, 21224
Contact: Rebecca Ozl, CRC 410-550-6492

Principal Investigator: Alan Baer, MD

United States, New York
University of Rochester Medical Center Recruiting
Rochester, New York, United States, 14642

Contact: Debbie Campbell, RN 585-275-1635

Principal Investigator: Andreea Coca, MD
United States, North Carolina
Duke University Medical Center Recruiting
Durham, North Carolina, United States, 27710

Contact: Edna Scarlett 919-684-6150

Contact: Gary McDaniel, PA-C (919) 681-5871

Principal Investigator: E. William St. Clair, MD
United States, Oklahoma
Oklahoma Medical Research Foundation Recruiting
Oklahoma City, Oklahoma, United States, 73104

Contact: Virginia Roberts, LPN 405-271-7221

Principal Investigator: Judith James, MD, PhD
United States, Pennsylvania
University of Pittsburgh Recruiting
Pittsburgh, Pennsylvania, United States, 15260

Contact: Kimberly Diamond 412-586-3546

Principal Investigator: Robin C. Domsic, MD
Sponsors and Collaborators
Study Chair: E. William St. Clair, MD Duke University
Study Chair: Judith A. James, MD Oklahoma Medical Research Foundation
More Information

No publications provided

Responsible Party: National Institute of Allergy and Infectious Diseases (NIAID) Identifier: NCT01552681 History of Changes
Other Study ID Numbers: DAIT ASJ02
Study First Received: March 9, 2012
Last Updated: February 25, 2014
Health Authority:

United States: Food and Drug Administration

Good info, mads, thanks!

You are so welcome. Good luck to everyone wishing to take part!