Prescribed information for dryness?

I met with my Rheumy yesterday in an effort to find help for possible Sjogrens. HE LISTENS BUT DOES NOT HAVE A WARM FUZZY APPROACH. He prescribed Salazar and after reading the label, I am Leary about taking it. I also have FM and I am concerned about the fact that I am intolerant of heat and it always made me prespire greatly. I noticed that since this syndrome started I heat up but I have not personified the same way, les. Please post any ideas experiences or side effects experienced before I start it.

I can't find "side effects" of this little known drug on-line. I am allergic to only one type of drug: Sulfa and anything sulfate related, so I would never use this. Is there anyone out there who knows more about "Salazar" (even the name is strange)!?!

Is the drug you're referring to called "Salagen" (pilocarpine is the generic name)?

I just did some research on www.rxlist.com and discovered that most of the 'less' serious side affects are the same symptoms Sjogren's cause, so why would you even want to take it??? http://www.rxlist.com/salagen-side-effects-drug-center.htm

Yep there is a salazar.

Salagen has no side effects for me. It is mostly for the dry mouth, which is not my main problem. It doesn't help the overall dryness in other parts of the body. It makes you produce more saliva. Can't tell that it helps the dry eyes.

Anna,

Well I take Salagen also known as Pilocarpine, which stimulates the glands that do function, to produce more moisture. Manly thought of for dry mouth and dry eyes, but it is a systemic medication so it works everywhere.

Sometimes it makes me very hot and sweaty but it doesn't last much more than 30 mins or so.

I looked up Salazar on this website:
http://www.mims.com/India/patientmedicine/info/SALAZAR%20enteric-coated%20tab/Sulfasalazine

I think you should ask a Dr. some more questions before to agreeing to take it.

It is used for inflammatory issues which would make some sense. But it also says you should have regular blood test to keep an eye on your kidney and liver function. Apparently this medication could have some damaging effects, though it doesn't go into details.

It's the kidneys that make me take pause. The kidneys need a lot of water. I have had several kidney stones and I've discovered that is primarily caused by a lack of water. Since SS is all about the body not producing enough water, I see a little red flag go up every time the kidneys come up. If you think you may have SS, then I'd be careful.

In might not be a problem, but I'd ask some questions anyway.

If you don't like this Dr. you should look for another one. At the same time be prepared that Dr.s will not jump to give you a SS diagnosis. Typically we have to have symptoms for several years and the Dr. will probably want to see you for a minimum of a year before they will even consider giving a SS diagnosis. It's not something they can just do a test or two and announce you have it. So they really don't like to say anyone has it.

Josh



joshedu said:

Anna,

Well I take Salagen also known as Pilocarpine, which stimulates the glands that do function, to produce more moisture. Manly thought of for dry mouth and dry eyes, but it is a systemic medication so it works everywhere.

Sometimes it makes me very hot and sweaty but it doesn't last much more than 30 mins or so.

I looked up Salazar on this website:
http://www.mims.com/India/patientmedicine/info/SALAZAR%20enteric-co...

I think you should ask a Dr. some more questions before to agreeing to take it.

It is used for inflammatory issues which would make some sense. But it also says you should have regular blood test to keep an eye on your kidney and liver function. Apparently this medication could have some damaging effects, though it doesn't go into details.

It's the kidneys that make me take pause. The kidneys need a lot of water. I have had several kidney stones and I've discovered that is primarily caused by a lack of water. Since SS is all about the body not producing enough water, I see a little red flag go up every time the kidneys come up. If you think you may have SS, then I'd be careful.

In might not be a problem, but I'd ask some questions anyway.

If you don't like this Dr. you should look for another one. At the same time be prepared that Dr.s will not jump to give you a SS diagnosis. Typically we have to have symptoms for several years and the Dr. will probably want to see you for a minimum of a year before they will even consider giving a SS diagnosis. It's not something they can just do a test or two and announce you have it. So they really don't like to say anyone has it.

Josh



Della said:

Salagen has no side effects for me. It is mostly for the dry mouth, which is not my main problem. It doesn't help the overall dryness in other parts of the body. It makes you produce more saliva. Can't tell that it helps the dry eyes.



Anna Banana said: Thanks Della! I will post after I try it, plan to pick it up tomorrow!



Della said:

Salagen has no side effects for me. It is mostly for the dry mouth, which is not my main problem. It doesn't help the overall dryness in other parts of the body. It makes you produce more saliva. Can't tell that it helps the dry eyes.

A recent post stated that there is a new blood test to diagnose Sjogren"s Syndrome; when switching to a new doctor I would have him/her to look into this test.

joshedu said:

Anna,

Well I take Salagen also known as Pilocarpine, which stimulates the glands that do function, to produce more moisture. Manly thought of for dry mouth and dry eyes, but it is a systemic medication so it works everywhere.

Sometimes it makes me very hot and sweaty but it doesn't last much more than 30 mins or so.

I looked up Salazar on this website:
http://www.mims.com/India/patientmedicine/info/SALAZAR%20enteric-co...

I think you should ask a Dr. some more questions before to agreeing to take it.

It is used for inflammatory issues which would make some sense. But it also says you should have regular blood test to keep an eye on your kidney and liver function. Apparently this medication could have some damaging effects, though it doesn't go into details.

It's the kidneys that make me take pause. The kidneys need a lot of water. I have had several kidney stones and I've discovered that is primarily caused by a lack of water. Since SS is all about the body not producing enough water, I see a little red flag go up every time the kidneys come up. If you think you may have SS, then I'd be careful.

In might not be a problem, but I'd ask some questions anyway.

If you don't like this Dr. you should look for another one. At the same time be prepared that Dr.s will not jump to give you a SS diagnosis. Typically we have to have symptoms for several years and the Dr. will probably want to see you for a minimum of a year before they will even consider giving a SS diagnosis. It's not something they can just do a test or two and announce you have it. So they really don't like to say anyone has it.

Josh

A.Banana,

I left my doctor, who is the foremost specialist in Sjogrens in the US, but her "thing" is prescribing drugs (a cocktail if you will) and she "looks" interested, but she is not really listening because when I got my file from her I found she wrote things with her own "spin" on what I was reporting to her. I have a question: this ex-rheumy prescribed Plaquinil, which did not agree with me, so she then prescribed Cellcept! Have any of you been prescribed this drug for SS?!

I want to clarify my comments on Salagen. I know the Salagen increases my saliva production because it's too obvious to miss. I have experienced being hot and sweaty as well. I haven't noticed any change in my eyes when I take it.

I cannot say if the Salagen also helps skin or organs. I would assume that it would get all the glands to produce more, but I can't say that for sure.

I've made the assumption that the Salagen helps other parts of the body that you don't really notice (like organs). But again, that's just an assumption.

Josh

I’m new to this site, I used Salagen for awhile but didn’t like the feeling it gave me, sweaty but also a skin crawling feeling, if I had noticed results I would have continued but I didn’t see any improvement so I stopped.

Usually Plaquenil is first line for sjogrens not salazar. If you're in the states you can get either salagen or evoxac to help with the dry mouth. Canada only has Salagen. Sometimes they help some with the dry eyes too. Evoxac is more specific so less side effects, lasts longer too but some people report no side effects with salagen which doesn't last as long but has a faster onset of action.

Hi Anna Banana,

You mention that you 'heat up', I have Sjogrens, Fibro, but am always cold, of course I also have PsA and Raynaud's which makes me more cold intolerant! I actually sweat more than I'm cold that when I'm hot! How backward is that?

I posted a discussion about autonomic system dysfunction, and profuse sweating was one of the 4 that clicked with me, so I guess I must have this dysfunction!

As much as we are all alike, we are also so different!

I hope you can get to a good place with the meds! :)

Thanks

I know we are all so different. They are delivering the meds maybe Monday so I will try it to see if I get any results good or bad and will report of it.

Thanks! How often do you take it? I read that it takes 12 weeks to notice the difference. I am on day two but only tried once a day at bedtime The MD said 3 times a day. When I woke up this AM I think my eyes felt a little less dry but nit SURE if I dreamt it as I was waking up.