Bloodwork negative but possible kidney issues

I have been diagnosed with Sjogren’s syndrome 2014. I have been tested regularly since then and positives every time. Always the same number of ANA. This time it came back negative and no inflammation every time. Although I did show possible kidney issues.

I have been feeling a flare (irritated/dry eyes, dry skin, thin hair, fatigue, brain fog…etc) and have read that a flare can cause antibodies to fluctuate and sometimes look like they are normal. I left a message with the Dr’s office to explain the results to me. In the meantime, I thought I would consult the sjogren’s peeps internet oracle! Has anyone ever had this occur? What does it mean when you are suddenly negative for autoimmune disease?

Interesting. But considering how hard it can be to catch, it almost doesn’t surprise me that you are having that happen.